Amidst the disrupting circumstances resulting from the global pandemic COVID-19, this new study provides a comprehensive overview of the evolution of the COVID-19 pandemic in the Mediterranean and Africa, policy and economic responses to curb it and to alleviate the socio-economic negative consequences. Lead author of the study is the President of EMEA and Director of EMNES, Prof Rym Ayadi, with contributions from EMEA researchers Giovanni Barci and Sara Ronco. The study provides the description of the EMEA COVID-19 Monitor Platform and the main findings from the monitoring implemented from the beginning of the pandemic till 24 September 2020. The Monitor, launched in June 2020, is composed of different sections, following the three pillars proposed by EMEA in its first study on COVID-19 ,  launched on 22 April 2020. After several months of observations, the new study provides a preliminary assessment of the COVID-19 evolution, containment and de-containment measures and the socio-economic preparedness and policies adopted to mitigate the impact of the pandemic. The study is part of the EMEA policy research initiative on COVID-19 launched on March 18th, 2020. The initiative provides up-to-date research on COVID-19 related topics, publishes studies, data and policy papers and organizes webinars to discuss the outcomes. It is led and coordinated by Prof. Rym Ayadi, President of EMEA and Director of EMNES. Since events surrounding COVID-19 are unfolding at the time of writing, EMEA research team and EMNES researchers and fellows continue updating the data, policy developments and the economic and social consequences of the pandemic throughout the Mediterranean and Africa. The updates are posted regularly on the EMEA platform. EMEA COVID-19 Tracker: https://research.euromed-economists.org/covid-19/ The Tracker collects automatically daily data from international institutions (e.g. WHO, OECD, IMF..) on the COVID-19 pandemic via a built-in algorithm. EMEA COVID-19 Monitor: https://research.euromed-economists.org/introduction/ The Monitor provides weekly assessments of the COVID-19 evolutions and EMEA analysis on the topic.